Disclosed herein are system and method for controlling an unmanned aerial vehicle (UAV) tethered from a mobile platform, the UAV system comprising: a UAV comprising one or more sensors, and one or more propellers; a tether attached to the UAV and to the mobile platform; a digital processing device comprising an operating system configured to perform executable instructions and a memory; and a computer program including instructions executable by the digital processing device to automatically control the UAV relative to the mobile platform comprising: a software module identifying the mobile platform; a software module estimating a real-time state of the mobile platform; and a software module automatically controlling three-dimensional real-time motion of the UAV based on the real-time state estimation of the mobile platform and data collected from the one or more sensors, such that the UAV is maintained at a predetermined position relative to the mobile platform.