- 专利标题： HETEROARYL-BIPHENYL AMIDES FOR THE TREATMENT OF PD-L1 DISEASES
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申请号： US17071077申请日： 2020-10-15
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公开(公告)号： US20210130325A1公开(公告)日： 2021-05-06
- 发明人: Pingchen FAN , Christopher W. LANGE , Rebecca M. LUI , Darren J. McMURTRIE , Ryan J. SCAMP , Ju YANG , Yibin ZENG , Penglie ZHANG
- 申请人： CHEMOCENTRYX, INC.
- 申请人地址： US CA Mountain View
- 专利权人： CHEMOCENTRYX, INC.
- 当前专利权人： CHEMOCENTRYX, INC.
- 当前专利权人地址： US CA Mountain View
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07D403/14 ; C07D405/14 ; C07D401/12 ; C07D487/10
摘要：
Compounds are provided that are useful as immunomodulators. The compounds have the Formula (I) including stereoisomers and pharmaceutically acceptable salts thereof, wherein R2a, R2b, R3, R3a, R4, R6, R7, R8, A, Z, X1 and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
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