- 专利标题： SPLICE VARIANTS ASSOCIATED WITH NEOMORPHIC SF3B1 MUTANTS
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申请号： US17098940申请日： 2020-11-16
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公开(公告)号： US20210130909A1公开(公告)日： 2021-05-06
- 发明人: Lihua Yu , Kian Huat Lim , Jacob D. Feala , Silvia Buonamici , Yoshiharu Mizui , Peter G. Smith , Ping Zhu , Eunice Sun Park , Michael W. Seiler , Marco Peter Fekkes
- 申请人： Eisai R&D Management Co., Ltd.
- 申请人地址： JP Tokyo
- 专利权人： Eisai R&D Management Co., Ltd.
- 当前专利权人： Eisai R&D Management Co., Ltd.
- 当前专利权人地址： JP Tokyo
- 主分类号： C12Q1/6886
- IPC分类号： C12Q1/6886 ; A61P35/00 ; A61K31/4545 ; A61K31/495 ; A61K31/55 ; C12Q1/02 ; C12Q1/6806
摘要：
Splice variants associated with neomorphic SF3B1 mutations are described herein. This application also relates to methods of detecting the described splice variants, and uses for diagnosing cancer, evaluating modulators of SF3B1, and methods of treating cancer associated with mutations in SF3B1.
公开/授权文献
- US11761045B2 Splice variants associated with neomorphic SF3B1 mutants 公开/授权日：2023-09-19
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