Invention Application
- Patent Title: Bubble-shaped adaptor element and method of constructing sequencing library with bubble-shaped adaptor element
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Application No.: US17172927Application Date: 2021-02-10
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Publication No.: US20210164042A1Publication Date: 2021-06-03
- Inventor: Yuan Jiang , Xia Zhao , Qiaoling Li , Shengmao Liu , Bo Wang , Li Chen , Wenwei Zhang , Hui Jiang , Radoje Drmanac
- Applicant: MGI TECH CO., LTD.
- Applicant Address: CN Shenzhen
- Assignee: MGI TECH CO., LTD.
- Current Assignee: MGI TECH CO., LTD.
- Current Assignee Address: CN Shenzhen
- Main IPC: C12Q1/6874
- IPC: C12Q1/6874 ; C12Q1/68 ; C12Q1/6869 ; C12Q1/6855

Abstract:
Provided are an adaptor element in a bubble shape, a method of constructing a sequencing library with such an adapter element. The adaptor element is a hybrid formed with a long-chain nucleic acid A and a short-chain nucleic acid B. The hybrid is in the bubble shape with paired regions at two terminals and a non-paired region in the middle.
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