Invention Application
- Patent Title: IMPROVED LIPID-PEPTIDE NANOCOMPLEX FORMULATION FOR MRNA DELIVERY TO CELLS
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Application No.: US16762886Application Date: 2018-11-09
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Publication No.: US20210170046A1Publication Date: 2021-06-10
- Inventor: Dania Grant-Serroukh , Stephen Lewis Hart
- Applicant: UCL Business Ltd
- Applicant Address: GB London
- Assignee: UCL Business Ltd
- Current Assignee: UCL Business Ltd
- Current Assignee Address: GB London
- Priority: GB1718660.2 20171110
- International Application: PCT/GB2018/053253 WO 20181109
- Main IPC: A61K47/69
- IPC: A61K47/69 ; A61K9/127 ; A61K47/54 ; A61K47/64 ; C12N15/88
Abstract:
A liposome comprising a cationic lipid, a phospholipid and a peptide and optionally consisting of from 20 to 50% by molarity cholesterol, based on the total amount of lipids, for use in non-viral gene delivery systems, for example, in the formation of lipopolyplex transfection vectors for the delivery of mRNA to cells.
Information query
