- 专利标题： METHODS FOR IMPROVING PURITY OF TENOFOVIR DISOPROXIL FUMARATE, AND COMPOSITIONS THEREOF
-
申请号： US17105017申请日： 2020-11-25
-
公开(公告)号： US20210171556A1公开(公告)日： 2021-06-10
- 发明人: John JACOBSEN , Valerie CALDWELL , Chris DICUS , Patrick BERGET
- 申请人： AMPAC Fine Chemicals LLC
- 申请人地址： US CA Rancho Cordova
- 专利权人： AMPAC Fine Chemicals LLC
- 当前专利权人： AMPAC Fine Chemicals LLC
- 当前专利权人地址： US CA Rancho Cordova
- 主分类号： C07F9/6561
- IPC分类号： C07F9/6561 ; G01N33/94 ; B01D3/36
摘要：
Methods for producing tenofovir disoproxil fumarate with improved purity are provided. In particular, methods for producing tenofovir disoproxil fumarate with reduced levels of chloromethyl isopropyl carbonate are described. Also described are compositions containing tenofovir disoproxil fumarate with improved purity, and an analysis method that can be used to determine the purity of such compositions with improved accuracy and sensitivity.
信息查询
