- 专利标题: GENOMIC SAFE HARBORS FOR GENETIC THERAPIES IN HUMAN STEM CELLS AND ENGINEERED NANOPARTICLES TO PROVIDE TARGETED GENETIC THERAPIES
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申请号: US16619211申请日: 2018-06-05
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公开(公告)号: US20210171983A1公开(公告)日: 2021-06-10
- 发明人: Jennifer E. Adair , Reza Shahbazi
- 申请人: FRED HUTCHINSON CANCER RESEARCH CENTER
- 申请人地址: US WA Seattle
- 专利权人: FRED HUTCHINSON CANCER RESEARCH CENTER
- 当前专利权人: FRED HUTCHINSON CANCER RESEARCH CENTER
- 当前专利权人地址: US WA Seattle
- 国际申请: PCT/US2018/036154 WO 20180605
- 主分类号: C12N15/90
- IPC分类号: C12N15/90 ; C12N15/113 ; C12N9/22 ; C12N5/078 ; A61K47/69
摘要:
Genomic safe harbors (GSH) for genetic therapies in human stem cells and engineered nanoparticles to provide targeted genetic therapies are described. The GSH and/or associated nanoparticles can be used to safely and efficiently treat a variety of genetic, infectious, and malignant diseases.
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