![Pharmaceutical formulations comprising 5-Chloro-N4-[2-(dimethylphosphoryl)phenyl]-N2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine](/docs/US/2021-06-24/US20210186994A1/abs.jpg.600x600.jpg)
- 专利标题： Pharmaceutical formulations comprising 5-Chloro-N4-[2-(dimethylphosphoryl)phenyl]-N2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine
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申请号： US17193502申请日： 2021-03-05
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公开(公告)号： US20210186994A1公开(公告)日： 2021-06-24
- 发明人: Dauntel S. Verwijs , Samir Desai , Pradeep K. Sharma , Leonard W. Rozamus , Jeff Williamson , Danica Cartwright , Parag Ved
- 申请人： Ariad Pharmaceuticals, Inc.
- 申请人地址： US MA Cambridge
- 专利权人： Ariad Pharmaceuticals, Inc.
- 当前专利权人： Ariad Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 主分类号： A61K31/675
- IPC分类号： A61K31/675 ; A61K9/20 ; A61K9/28 ; A61K31/662 ; A61P35/00
![Pharmaceutical formulations comprising 5-Chloro-N4-[2-(dimethylphosphoryl)phenyl]-N2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine](/abs-image/US/2021/06/24/US20210186994A1/abs.jpg.150x150.jpg)
摘要：
This invention relates to a pharmaceutical composition comprising 5-chloro-N4-[2-(dimethylphosphoryl)phenyl]-N2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine as the active pharmaceutical ingredient, and therapeutic uses of the pharmaceutical formulation. In particular, the invention is directed to tablets comprising the pharmaceutical composition, methods of preparing the tablets, and therapeutic uses thereof.
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