- 专利标题： ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE
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申请号： US17058481申请日： 2019-05-24
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公开(公告)号： US20210198213A1公开(公告)日： 2021-07-01
- 发明人: Han-Jie Zhou , Peter Virsik , Raymond John Andersen , Marianne Dorothy Sadar , Kunzhong Jian , Daniel Andrew Golec
- 申请人： ESSA Pharma, Inc. , The University of British Columbia , Provincial Health Services Authority
- 申请人地址： CA Vancouver; CA Vancouver; CA Vancouver
- 专利权人： ESSA Pharma, Inc.,The University of British Columbia,Provincial Health Services Authority
- 当前专利权人： ESSA Pharma, Inc.,The University of British Columbia,Provincial Health Services Authority
- 当前专利权人地址： CA Vancouver; CA Vancouver; CA Vancouver
- 国际申请： PCT/US2019/033921 WO 20190524
- 主分类号： C07D239/34
- IPC分类号： C07D239/34 ; C07C317/28 ; C07D305/06 ; C07D295/26 ; C07C317/24 ; C07C69/712 ; C07D263/56 ; C07D207/24 ; C07C235/74 ; A61K45/06
摘要：
Compounds having a structure of formula (I), (I-A), (Ia)-(Ie), (A)-(E), and (II) or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof are provided. Uses of such compounds for modulating androgen receptor activity, imaging diagnostics in cancer and therapeutics, and methods for treatment of disorders including prostate cancer are also provided.
公开/授权文献
- US11485713B2 Androgen receptor modulators and methods for their use 公开/授权日：2022-11-01
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