- 专利标题： MEBENDAZOLE PRODRUGS WITH ENHANCED SOLUBILITY AND ORAL BIOAVAILABILITY
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申请号： US16967924申请日： 2019-02-08
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公开(公告)号： US20210205271A1公开(公告)日： 2021-07-08
- 发明人: Barbara Slusher , Rana Rais , Gregory Riggins , Pavel Majer , Tomas Tichy , Jan Vavra , Andrej Jancarik
- 申请人： The Johns Hopkins University , Institute of Organic Chemistry and Biochemistry AS CR v.v.i.
- 申请人地址： US MD Baltimore; CZ Prague
- 专利权人： The Johns Hopkins University,Institute of Organic Chemistry and Biochemistry AS CR v.v.i.
- 当前专利权人： The Johns Hopkins University,Institute of Organic Chemistry and Biochemistry AS CR v.v.i.
- 当前专利权人地址： US MD Baltimore; CZ Prague
- 国际申请： PCT/US2019/017291 WO 20190208
- 主分类号： A61K31/4184
- IPC分类号： A61K31/4184 ; A61K45/06 ; C07D235/32 ; C07H15/26 ; C07F9/6506 ; A61K31/7056 ; A61K31/675 ; A61K31/685 ; C07D405/12
摘要：
Prodrugs of mebendazole and methods for their use in treating a disease, disorder, or disorder, including cancer, are disclosed.
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