- 专利标题： CARBOXYESTERASE POLYPEPTIDES FOR AMIDE COUPLING
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申请号： US17236928申请日： 2021-04-21
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公开(公告)号： US20210238565A1公开(公告)日： 2021-08-05
- 发明人: Rama Voladri , David Entwistle , Christopher Michael Micklitsch , Vesna Mitchell , Nikki Dellas , Xiyun Zhang , Antoinette Sero , Brent Dorr , Douglas E. Fuerst
- 申请人： Codexis, Inc.
- 申请人地址： US CA Redwood City
- 专利权人： Codexis, Inc.
- 当前专利权人： Codexis, Inc.
- 当前专利权人地址： US CA Redwood City
- 主分类号： C12N9/18
- IPC分类号： C12N9/18
摘要：
The present invention provides engineered carboxyesterase enzymes having improved properties as compared to a naturally occurring wild-type carboxyesterase enzymes, as well as polynucleotides encoding the engineered carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes in amidation reactions.
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