- 专利标题： COMPOSITIONS COMPRISING METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME
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申请号： US17240181申请日： 2021-04-26
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公开(公告)号： US20210253552A1公开(公告)日： 2021-08-19
- 发明人: Travis Mickle , Sven Guenther , Guochen Chi
- 申请人： KemPharm, Inc.
- 申请人地址： US FL Celebration
- 专利权人： KemPharm, Inc.
- 当前专利权人： KemPharm, Inc.
- 当前专利权人地址： US FL Celebration
- 主分类号： C07D401/12
- IPC分类号： C07D401/12 ; A61K9/00 ; C07D211/34 ; A61K31/4545 ; A61K47/54 ; A61K31/4458
摘要：
The present technology is directed to d-threo-methylphenidate conjugates and a composition comprising d-threomethylphenidate conjugated to nicotinoyl-L-serine, or salt thereof. The present technology also relates to a composition comprising at least one conjugate of d-methylphenidate having at least two or more chiral centers. The composition is optically active. The present technology additionally relates to oral formulations and pharmaceutical kits comprising at least one d-threo-methylphenidate conjugate.
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