- 专利标题： PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MEDIATED DISEASES
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申请号： US17204679申请日： 2021-03-17
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公开(公告)号： US20210308053A1公开(公告)日： 2021-10-07
- 发明人: Brian Dean Phenix , Laurent Jean-Claude Bagnol , Geoffrey Glen Brodeur , Sachin Chandran , Eleni Dokou , Lori Ann Ferris , Dragutin Knezic , Katie Lynn McCarty , Ales Medek , Sara A. Waggener
- 申请人： Vertex Pharmaceuticals Incorporated
- 申请人地址： US MA Boston
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： US MA Boston
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; A61K9/16 ; A61K45/06 ; A61K9/20 ; A61K31/404 ; A61K31/47 ; C07D215/00 ; C07D209/04 ; C07D215/56 ; C07D405/12 ; A61K31/443 ; A61K31/4709 ; A61K31/4725
摘要：
The present invention features compositions comprising a plurality of therapeutic agents wherein the presence of one therapeutic agent enhances the properties of at least one other therapeutic agent. In one embodiment, the therapeutic agents are cystic fibrosis transmembrane conductance regulators (CFTR) such as a CFTR corrector or CFTR potentiator for the treatment of CFTR mediated diseases such as cystic fibrosis. Methods and kits thereof are also disclosed.
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