- 专利标题： METHOD FOR PRODUCING INTESTINAL CELLS FROM PLURIPOTENT STEM CELLS
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申请号： US17274543申请日： 2019-09-09
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公开(公告)号： US20210340500A1公开(公告)日： 2021-11-04
- 发明人: Shoen KUME , Nobuaki SHIRAKI , Kazuya MAEDA , Hiroyuki KUSUHARA , Masaya ISHIKAWA , Teruhiko WATANABE
- 申请人： TOKYO INSTITUTE OF TECHNOLOGY , THE UNIVERSITY OF TOKYO , KANTO KAGAKU KABUSHIKI KAISHA
- 申请人地址： JP Tokyo; JP Tokyo; JP Tokyo
- 专利权人： TOKYO INSTITUTE OF TECHNOLOGY,THE UNIVERSITY OF TOKYO,KANTO KAGAKU KABUSHIKI KAISHA
- 当前专利权人： TOKYO INSTITUTE OF TECHNOLOGY,THE UNIVERSITY OF TOKYO,KANTO KAGAKU KABUSHIKI KAISHA
- 当前专利权人地址： JP Tokyo; JP Tokyo; JP Tokyo
- 优先权： JP2018-168957 20180910,JP2019-117748 20190625
- 国际申请： PCT/JP2019/035358 WO 20190909
- 主分类号： C12N5/071
- IPC分类号： C12N5/071
摘要：
As a method for producing enterocytes derived from pluripotent stem cells and having functions corresponding to those of actual enterocytes, a method for producing enterocytes using an enterocyte differentiation medium containing a GSK3 inhibitor, and at least one selected from the group consisting of an activator of a hepatocyte growth factor receptor, an adrenal cortex hormone, calcitriol, and dimethyl sulfoxide is provided.
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