- 专利标题： COMBINATION THERAPY USING ASCOCHLORIN DERIVATIVE
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申请号： US16613958申请日： 2018-05-18
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公开(公告)号： US20210346390A1公开(公告)日： 2021-11-11
- 发明人: Tatsuo HOSHINO , Shinji KAGAYA , Nobuo SHIMMA , Tsutomu KAWAGUCHI
- 申请人： Tatsuo HOSHINO
- 申请人地址： JP Kanagawa
- 专利权人： Tatsuo HOSHINO
- 当前专利权人： Tatsuo HOSHINO
- 当前专利权人地址： JP Kanagawa
- 优先权： JP2017-098860 20170518
- 国际申请： PCT/JP2018/020087 WO 20180518
- 主分类号： A61K31/5375
- IPC分类号： A61K31/5375 ; A61K31/122 ; A61K31/055 ; A61K31/15 ; A61K31/215 ; A61K31/495 ; A61K31/337 ; C07K16/28 ; A61P35/00
摘要：
An object of the present invention is to provide a measure for treating or preventing a disease or condition that involves AMPK dysregulation, particularly a cancer. The present invention provides a combination therapy using a compound presented by formula (I), a pharmaceutically acceptable salt or a solvate thereof with an immune checkpoint inhibitor.
公开/授权文献
- US11298358B2 Combination therapy using ascochlorin derivative 公开/授权日：2022-04-12