- 专利标题： BISPECIFIC T CELL ACTIVATING ANTIGEN BINDING MOLECULES
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申请号： US17443893申请日： 2021-07-28
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公开(公告)号： US20210355234A1公开(公告)日： 2021-11-18
- 发明人: Christian KLEIN , Marina BACAC , Anne FREIMOSER-GRUNDSCHOBER , Sylvia HERTER , Joaquin ARRIBAS , Rocio VICARIO
- 申请人： Hoffmann-La Roche Inc.
- 申请人地址： US NJ Little Falls
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Little Falls
- 优先权： EP16191933.7 20160930
- 主分类号： C07K16/32
- IPC分类号： C07K16/32 ; C07K16/28 ; C07K16/30 ; C07K16/46 ; A61P35/00
摘要：
The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.
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