发明申请
- 专利标题: ANTI-AXL ANTIBODIES, ANTIBODY FRAGMENTS AND THEIR IMMUNOCONJUGATES AND USES THEREOF
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申请号: US17465968申请日: 2021-09-03
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公开(公告)号: US20210403577A1公开(公告)日: 2021-12-30
- 发明人: Jay M. Short , Hwai Wen Chang , Gerhard Frey
- 申请人: BioAtla, Inc.
- 申请人地址: US CA San Diego
- 专利权人: BioAtla, Inc.
- 当前专利权人: BioAtla, Inc.
- 当前专利权人地址: US CA San Diego
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61K47/68 ; A61K47/65 ; A61P35/00
摘要:
An antibody or antibody fragment having a heavy chain variable region and/or light chain variable region that specifically binds to Axl protein. Immuoconjugages, pharmaceutical compositions and kits comprising the antibodies and antibody fragments are also provided. Also disclosed are methods of treating Axl-expressing cancers using the antibodies, antibody fragments, immunoconjugates and pharmaceutical compositions of the present invention.
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