- 专利标题: HIGH STRENGTH INTRAOSSEOUS IMPLANTS
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申请号: US17476182申请日: 2021-09-15
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公开(公告)号: US20220000588A1公开(公告)日: 2022-01-06
- 发明人: Vagan TAPALTSYAN , Morshed KHANDAKER , Shahram RIAHINEZHAD , Rami Mohanad Mahdi ALKHALEELI , Niyaf Nidhal Kadhem ALKADHEM
- 申请人: UNIVERSITY OF CENTRAL OKLAHOMA
- 申请人地址: US OK Edmond
- 专利权人: UNIVERSITY OF CENTRAL OKLAHOMA
- 当前专利权人: UNIVERSITY OF CENTRAL OKLAHOMA
- 当前专利权人地址: US OK Edmond
- 主分类号: A61C8/02
- IPC分类号: A61C8/02 ; A61K6/891 ; A61K6/898 ; A61C13/00 ; A61C8/00
摘要:
The present invention enables modification of an intraosseous implant device that is not only biologically non-inert, but can stimulate bone and vascular growth; decrease localized inflammation; and fight local infections. The method of the present invention provides a fiber with any of the following modifications: (1) Nanofiber with PDGF, (2) Nanofiber with PDGF+BMP2, and (3) Nanofiber with BMP2 and Ag. Nanofiber can be modified with other growth factors that have been shown to improve bone growth and maturation—BMP and PDGF being the most common. Nanofiber can be applied on the surface of the implant in several ways. First, a spiral micro-notching can be applied on the implant in the same direction as the threads with the nanofibers embedded into the notches. Second, the entire surface of the implant may be coated with a mesh of nanofibers. Third, it can be a combination of both embedding and notching.