- 专利标题: ANTIVIRAL AGENTS FOR TREATMENT OF CORONAVIRUSES
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申请号: US17244272申请日: 2021-04-29
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公开(公告)号: US20220000904A1公开(公告)日: 2022-01-06
- 发明人: Donald J. ALCENDOR
- 申请人: Meharry Medical College
- 申请人地址: US TN Nashville
- 专利权人: Meharry Medical College
- 当前专利权人: Meharry Medical College
- 当前专利权人地址: US TN Nashville
- 主分类号: A61K31/7125
- IPC分类号: A61K31/7125 ; A61K47/64 ; A61P31/14
摘要:
An antiviral agent is provided, having a phosphorodiamidate morpholino oligomer with an antisense sequence to a portion of a genome of a strain of a coronavirus. The coronavirus may be SARS-CoV-2 or another βCoV. The antiviral agent finds many uses, such as in a pharmaceutical composition, a method of treating coronavirus-mediated disease, a method of preventing coronavirus-mediated disease, a method of reducing or preventing the replication of coronavirus in a host cell, a method of controlling the spread of coronavirus in donated tissue, a treated tissue sample, and in the manufacture of a medicament for the treatment or prevention or coronavirus-mediated disease.