Invention Application
- Patent Title: PIGMENTATION SKIN MODEL AND METHOD FOR PRODUCING SAME, AND METHOD FOR EVALUATING FACTOR FOR TREATING OR PREVENTING PIGMENTATION OF SKIN
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Application No.: US17298446Application Date: 2019-11-29
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Publication No.: US20220025337A1Publication Date: 2022-01-27
- Inventor: Shoko YAMADA , Sayaka KOIDE , Masaya TAKAGI , Tsutomu SOMA , Kenta FUKUMURA
- Applicant: Shiseido Company, Ltd.
- Applicant Address: JP Chuo-ku, Tokyo
- Assignee: Shiseido Company, Ltd.
- Current Assignee: Shiseido Company, Ltd.
- Current Assignee Address: JP Chuo-ku, Tokyo
- Priority: JP2018-226024 20181130
- International Application: PCT/JP2019/046886 WO 20191129
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12N5/077 ; G01N33/50

Abstract:
The present invention provides a pigmentation skin model that comprises: a first cell group containing fibroblasts damaged by light irradiation, said first cell group being seeded on a first cell culture substratum; and a second cell group containing melanocytes and keratinocytes, said second cell group being applied onto the first cell group. The present invention also provides a method for producing the pigmentation skin model, and a method for evaluating a factor for treating or preventing pigmentation of the skin, said method comprising using the pigmentation skin model.
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