- 专利标题： QUANTITATIVE REGULATION OF A G PROTEIN SIGNALLING PATHWAY
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申请号： US17277672申请日： 2019-09-24
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公开(公告)号： US20220031864A1公开(公告)日： 2022-02-03
- 发明人: Robert Lucas , Jessica Rodgers
- 申请人： THE UNIVERSITY OF MANCHESTER
- 申请人地址： GB Manchester Greater Manchester
- 专利权人： THE UNIVERSITY OF MANCHESTER
- 当前专利权人： THE UNIVERSITY OF MANCHESTER
- 当前专利权人地址： GB Manchester Greater Manchester
- 优先权： GB1815513.5 20180924,GB1904631.7 20190402
- 国际申请： PCT/GB2019/052685 WO 20190924
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C07K14/46 ; A61P27/02 ; G01N33/50
摘要：
The present invention relates to methods of regulating G protein activity, and related methods for the treatment of therapeutic conditions, for example retinal degeneration, by transforming a cell with a bistable opsin to activate a G protein, and provide a phototransduction response.
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