Invention Application
- Patent Title: PYRROLOTRIAZINONES AND IMIDAZOTRIAZINONES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS
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Application No.: US17230603Application Date: 2021-04-14
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Publication No.: US20220033403A1Publication Date: 2022-02-03
- Inventor: Stephanos Ioannidis , Adam Charles Talbot , Bruce Follows , Alexandre Joseph Buckmelter , Minghua Wang , Ann-Marie Campbell
- Applicant: Valo Health, Inc.
- Applicant Address: US MA Boston
- Assignee: Valo Health, Inc.
- Current Assignee: Valo Health, Inc.
- Current Assignee Address: US MA Boston
- Main IPC: C07D487/04
- IPC: C07D487/04
Abstract:
The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where R1, R2, R3, R4, R5, R5′, R6, X1, X2, m, and n are described herein.
Public/Granted literature
- US11795171B2 Pyrrolotriazinones and imidazotriazinones as ubiquitin-specific protease 7 inhibitors Public/Granted day:2023-10-24
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