- 专利标题： FUNCTIONALIZATION OF ENDOGENOUS BACTERIA
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申请号： US17189113申请日： 2021-03-01
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公开(公告)号： US20220033830A1公开(公告)日： 2022-02-03
- 发明人: Timothy Kuan-Ta Lu , Robert James Citorik , James Collins , Russell-John Krom
- 申请人： Trustees of Boston University , Massachusetts Institute of Technology
- 申请人地址： US MA Boston; US MA Cambridge
- 专利权人： Trustees of Boston University,Massachusetts Institute of Technology
- 当前专利权人： Trustees of Boston University,Massachusetts Institute of Technology
- 当前专利权人地址： US MA Boston; US MA Cambridge
- 主分类号： C12N15/74
- IPC分类号： C12N15/74 ; C12N7/00 ; C12N15/70
摘要：
Various aspects and embodiments of the present disclosure are directed to methods and compositions for functionalizing endogenous bacteria in vivo. The methods include delivering to endogenous bacterial cells a recombinant bacteriophage or phagemid that is engineered to contain at least one genetic circuit.
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