Invention Application
- Patent Title: ANDROGEN RECEPTOR PROTEIN DEGRADERS
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Application No.: US17420421Application Date: 2019-12-19
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Publication No.: US20220081435A1Publication Date: 2022-03-17
- Inventor: Shaomeng Wang , Xin Han , Chao Wang , Chong Qin , Weiguo Xiang , Tianfeng Xu , Chao-Yie Yang
- Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Applicant Address: US MI Ann Arbor
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee Address: US MI Ann Arbor
- International Application: PCT/US19/67313 WO 20191219
- Main IPC: C07D417/14
- IPC: C07D417/14 ; A61K47/55 ; A61K45/06

Abstract:
The present disclosure provides compounds represented by Formula (I): A-L-B (I), and the salts or solvates thereof, wherein A, L, and B are as defined in the specification. Compounds having Formula (I) are androgen receptor degraders useful for the treatment of cancer.
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