- 专利标题： FLUORINE-CONTAINING SUBSTITUTED BENZOTHIOPHENE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF
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申请号： US17420389申请日： 2019-12-31
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公开(公告)号： US20220089561A1公开(公告)日： 2022-03-24
- 发明人: Ao ZHANG , Meiyu GENG , Chunyong DING , Zuoquan XIE , Jian DING , Yan ZHANG , Ancheng SHEN , Xiyuan WANG
- 申请人： SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. , Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- 申请人地址： CN Shanghai; CN Pudong, Shanghai
- 专利权人： SHANGHAI HAIHE PHARMACEUTICAL CO., LTD.,Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- 当前专利权人： SHANGHAI HAIHE PHARMACEUTICAL CO., LTD.,Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- 当前专利权人地址： CN Shanghai; CN Pudong, Shanghai
- 优先权： CN201910002749.2 20190102
- 国际申请： PCT/CN2019/130605 WO 20191231
- 主分类号： C07D333/64
- IPC分类号： C07D333/64 ; C07D409/12
摘要：
A fluorine-containing substituted benzothiophene compound and a pharmaceutical composition and an application thereof are described. The compound has the structure as shown in formula (I), in which the definitions of each group and substituent are as described in the description. A preparation method of the compound and an anti-tumor application thereof are also described.