- 专利标题: QUANTITATIVE AUXILIARY-FREE CHIRALITY SENSING WITH A METAL PROBE
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申请号: US17275471申请日: 2019-09-11
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公开(公告)号: US20220113247A1公开(公告)日: 2022-04-14
- 发明人: Christian WOLF , Zeus A. O. DE LOS SANTOS , Ciaran LYNCH
- 申请人: GEORGETOWN UNIVERSITY
- 申请人地址: US DC Washington
- 专利权人: GEORGETOWN UNIVERSITY
- 当前专利权人: GEORGETOWN UNIVERSITY
- 当前专利权人地址: US DC Washington
- 国际申请: PCT/US19/50628 WO 20190911
- 主分类号: G01N21/19
- IPC分类号: G01N21/19 ; G01N21/77
摘要:
The present invention relates to an analytical method that includes providing a sample potentially containing a chiral analyte that can exist in stereoisomeric forms, and providing a probe selected from the group consisting of metal salts. The sample is contacted with the probe under conditions that permit coordination of the probe to the analyte, if present in the sample; and, based on any coordination that occurs, the absolute configuration of the analyte in the sample, and/or the concentration of the analyte in the sample, and/or the enantiomeric composition of the analyte in the sample is/are determined.