- 专利标题： LIPID PRODRUGS OF JAK INHIBITORS AND USES THEREOF
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申请号： US17310871申请日： 2020-02-28
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公开(公告)号： US20220125933A1公开(公告)日： 2022-04-28
- 发明人: Joseph BOLEN , Daniel Kenneth BONNER , Ketki KARANAM , Christopher John PORTER , Jamie SIMPSON , Natalie TREVASKIS , Dan ZHENG , Nathania LEONG , Garima SHARMA , Mitchell MCINERNEY , Tim QUACH , Sifei HAN
- 申请人： PureTech LYT, Inc. , Monash University
- 申请人地址： US MA Boston; AU Clayton, Victoria
- 专利权人： PureTech LYT, Inc.,Monash University
- 当前专利权人： PureTech LYT, Inc.,Monash University
- 当前专利权人地址： US MA Boston; AU Clayton, Victoria
- 国际申请： PCT/US2020/020398 WO 20200228
- 主分类号： A61K47/54
- IPC分类号： A61K47/54 ; A61K31/519 ; A61K31/529 ; A61K31/437 ; A61K31/4985 ; A61P35/00
摘要：
The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.
公开/授权文献
- US3863712A Liquid heat exchange system 公开/授权日：1975-02-04
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