Invention Application
- Patent Title: ANTIBODIES THAT SPECIFICALLY BIND TO HUMAN IL-15 AND USES THEREOF
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Application No.: US17647082Application Date: 2022-01-05
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Publication No.: US20220127352A1Publication Date: 2022-04-28
- Inventor: David Jose Simon LAINE , Matthew POLLARD , Anthony Gerard DOYLE , Lynn Dorothy POULTON , Adam William CLARKE
- Applicant: Cephalon, Inc.
- Applicant Address: US PA West Chester
- Assignee: Cephalon, Inc.
- Current Assignee: Cephalon, Inc.
- Current Assignee Address: US PA West Chester
- Main IPC: C07K16/24
- IPC: C07K16/24 ; A61P37/00 ; A61P3/00 ; A61P29/02 ; A61P1/00
Abstract:
Recombinant antibodies that specifically bind to IL-15 as well as a complex of IL-15 and the IL-15 Receptor-alpha are provided. The antibodies inhibit immune cell proliferation, and are capable of use in the treatment of any autoimmune or inflammatory disease or condition where IL-15 is dysregulated, including Celiac disease.
Information query
