- 专利标题: METHODS, COMPOSITIONS, KITS, AND USES FOR ANALYSIS OF NUCLEIC ACIDS COMPRISING REPEATING A/T-RICH SEGMENTS
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申请号: US17456204申请日: 2021-11-23
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公开(公告)号: US20220136044A1公开(公告)日: 2022-05-05
- 发明人: Gary J. Latham , Sachin Sah
- 申请人: Asuragen, Inc.
- 申请人地址: US TX Austin
- 专利权人: Asuragen, Inc.
- 当前专利权人: Asuragen, Inc.
- 当前专利权人地址: US TX Austin
- 主分类号: C12Q1/6844
- IPC分类号: C12Q1/6844
摘要:
Described herein are methods, compositions, kits, and uses thereof for analysis of nucleic acid segments comprising a repeating A/T-rich segment, wherein the repeating A/T-rich segment is: (i) a homopolymeric segment comprising at least 10 A residues, at least 10 T residues, or at least 10 U residues, wherein the at least 10 A, T, or U residues are consecutive or interrupted once by one to three other nucleotides; or (ii) a segment comprising (TnA)m, (ATn)m, (TAn)m, or (AnT)m, wherein n is 2 or greater and m is such that the length of the repeating A/T-rich segment is 10 or more residues.
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