Invention Application
- Patent Title: COMPOSITIONS FOR DELIVERY OF CODON-OPTIMIZED MRNA
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Application No.: US17522754Application Date: 2021-11-09
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Publication No.: US20220160633A1Publication Date: 2022-05-26
- Inventor: John Androsavich , Lianne Boeglin , Shraddha Sharma , Gang Sun , Neha Kaushal , Shrirang Karve
- Applicant: Translate Bio, Inc.
- Applicant Address: US MA Lexington
- Assignee: Translate Bio, Inc.
- Current Assignee: Translate Bio, Inc.
- Current Assignee Address: US MA Lexington
- Main IPC: A61K9/127
- IPC: A61K9/127 ; A61K31/7105 ; A61K9/00
Abstract:
The present invention provides, among other things, improved pharmaceutical compositions comprising codon-optimized mRNA encoding a peptide or polypeptide encapsulated in a lipid nanoparticle comprising one or more of the cationic lipids that are particularly effective for pulmonary delivery.
Information query
