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公开(公告)号：US20220160633A1
公开(公告)日：2022-05-26
申请号：US17522754
申请日：2021-11-09
Applicant: Translate Bio, Inc.
Inventor： John Androsavich , Lianne Boeglin , Shraddha Sharma , Gang Sun , Neha Kaushal , Shrirang Karve
IPC: A61K9/127 , A61K31/7105 , A61K9/00
Abstract: The present invention provides, among other things, improved pharmaceutical compositions comprising codon-optimized mRNA encoding a peptide or polypeptide encapsulated in a lipid nanoparticle comprising one or more of the cationic lipids that are particularly effective for pulmonary delivery.
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