- 专利标题： NOVEL INDOLIZINE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)
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申请号： US17607428申请日： 2020-04-29
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公开(公告)号： US20220227789A1公开(公告)日： 2022-07-21
- 发明人: Susanne BONSMANN , Alastair DONALD , Andreas URBAN , Jasper SPRINGER , Elena DETTA
- 申请人： AiCuris GmbH & Co. KG
- 申请人地址： DE Wuppertal
- 专利权人： AiCuris GmbH & Co. KG
- 当前专利权人： AiCuris GmbH & Co. KG
- 当前专利权人地址： DE Wuppertal
- 优先权： EP19172002.8 20190430,EP19172396.4 20190502
- 国际申请： PCT/EP2020/061946 WO 20200429
- 主分类号： C07D519/00
- IPC分类号： C07D519/00 ; C07D498/04 ; A61P31/20
摘要：
The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.
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