Invention Application
- Patent Title: OLIGONUCLEOTIDES FOR DGAT2 MODULATION
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Application No.: US17532636Application Date: 2021-11-22
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Publication No.: US20220228141A1Publication Date: 2022-07-21
- Inventor: Michael P. Czech , Batuhan Orbay Yenilmez , Anastasia Khvorova
- Applicant: UNIVERSITY OF MASSACHUSETTS
- Applicant Address: US MA Boston
- Assignee: UNIVERSITY OF MASSACHUSETTS
- Current Assignee: UNIVERSITY OF MASSACHUSETTS
- Current Assignee Address: US MA Boston
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K31/7088

Abstract:
This disclosure relates to novel DGAT2 targeting sequences. Novel DGAT2 targeting oligonucleotides for the treatment of non-alcoholic fatty liver disease (NAFLD) and lipodystrophy syndromes (or metabolic syndrome) are also provided.
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