Invention Application
- Patent Title: COMPOSITIONS AND METHODS FOR ORGAN SPECIFIC DELIVERY OF NUCLEIC ACIDS
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Application No.: US17711911Application Date: 2022-04-01
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Publication No.: US20220233460A1Publication Date: 2022-07-28
- Inventor: Qiang CHENG , Tuo WEI , Daniel J. SIEGWART
- Applicant: The Board of Regents of The University of Texas System
- Applicant Address: US TX Austin
- Assignee: The Board of Regents of The University of Texas System
- Current Assignee: The Board of Regents of The University of Texas System
- Current Assignee Address: US TX Austin
- Main IPC: A61K9/51
- IPC: A61K9/51 ; C12N9/22 ; C12N15/11 ; C12N15/113 ; A61K48/00
Abstract:
The present disclosure provides compositions which shown preferential targeting or delivery of a nucleic acid composition to a particular organ. In some embodiments, the composition comprises a steroid or sterol, an ionizable cationic lipid, a phospholipid, a PEG lipid, and a permanently cationic lipid which may be used to deliver a nucleic acid.
Public/Granted literature
- US11510880B2 Compositions and methods for organ specific delivery of nucleic acids Public/Granted day:2022-11-29
Information query
