The present disclosure provides a map data fusion method and apparatus, an electronic device, a medium and a program product. The method includes: acquiring first map data and second map data; based on a first feature descriptor set and a second feature descriptor set included in the first map data and the second map data respectively, determining a set of matching point pairs between a first set of three-dimensional coordinate points and a second set of three-dimensional coordinate points included in the first map data and the second map data respectively; determining a pose transformation matrix between the first map data and the second map data based on the set of matching point pairs; and fusing the first map data and the second map data into third map data based on the pose transformation matrix.