Techniques for predictive system remediation are disclosed. Based on attributes associated with applications of one or more system-selected remedial actions to one or more problematic system behaviors in a system (e.g., a database system), the system determines a predicted effectiveness of one or more future applications of a remedial action to a particular problematic system behavior, as of one or more future times. The system determines that the predicted effectiveness of the one or more future applications of the remedial action is positive but does not satisfy a performance criterion. Responsive to determining that the predicted effectiveness is positive but does not satisfy the performance criterion, the system generates a notification corresponding to the predicted effectiveness not satisfying the performance criterion. The system applies the remedial action to the particular problematic system behavior, despite already determining that the predicted effectiveness does not satisfy the one or more performance criteria.