- 专利标题: Compositions Comprising a Retinoid X Receptor (RXR) Agonist, a Retinoic Acid Receptor (RAR) Agonist, or a Dual RXR/RAR Agonist
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申请号: US17622915申请日: 2020-06-24
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公开(公告)号: US20220259157A1公开(公告)日: 2022-08-18
- 发明人: Carl Wagner , Pamela Marshall , Peter Jurutka
- 申请人: Carl Wagner , Pamela Marshall , Peter Jurutka
- 申请人地址: US AZ Glendale; US AZ Peoria; US AZ Scottsdale
- 专利权人: Carl Wagner,Pamela Marshall,Peter Jurutka
- 当前专利权人: Carl Wagner,Pamela Marshall,Peter Jurutka
- 当前专利权人地址: US AZ Glendale; US AZ Peoria; US AZ Scottsdale
- 国际申请: PCT/US2020/039337 WO 20200624
- 主分类号: C07D239/42
- IPC分类号: C07D239/42 ; C07D213/80 ; C07C229/60
摘要:
The present invention relates to compositions comprising an RXR agonist, an RAR agonist, or a dual RXR/RAR agonist. The present invention further relates to methods of using the agonist compositions for treating or preventing dementia and cancer. In some embodiments, the dementia comprises Alzheimer's disease. In some embodiments, the cancer comprises leukemia.
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