A bone fixation system includes a bone plate having an outer surface, an opposed bone-facing surface, and an interior surface that defines a hole extending from the outer surface to the bone-facing surface along a central hole axis. The interior surface further defines a compression surface. The system includes a bone fixation member having a shaft extending from a head along a central fixation member axis. The head has an exterior surface that defines a threaded head portion configured for variable angle locking with a complimentary variable angle plate locking structure. The compression surface and the threaded head portion are cooperatively configured to translate the bone plate in a direction substantially perpendicular to the central hole axis when the threaded head portion contacts the compression surface when the bone fixation member axis is offset from the central hole axis at an offset parameter as the head advances within the hole.