- 专利标题： High-Throughput Identification of Patient-Specific Neoepitopes as Therapeutic Targets for Cancer Immunotherapies
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申请号： US17740040申请日： 2022-05-09
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公开(公告)号： US20220270709A1公开(公告)日： 2022-08-25
- 发明人: Andrew Nguyen , John Zachary Sanborn , Stephen Charles Benz , Kayvan Niazi , Shahrooz Rabizadeh , Patrick Soon-Shiong , Charles Joseph Vaske
- 申请人： Nantomics LLC
- 申请人地址： US CA Culver City
- 专利权人： Nantomics LLC
- 当前专利权人： Nantomics LLC
- 当前专利权人地址： US CA Culver City
- 主分类号： G16B20/20
- IPC分类号： G16B20/20 ; G16B20/00 ; A61K35/17 ; A61K39/395 ; A61K48/00 ; C12Q1/6886 ; A61K47/68 ; A61K39/00 ; A61K45/06
摘要：
Systems and methods are presented that allow for selection of tumor neoepitopes that are filtered for various criteria. In particularly contemplated aspects, filtering includes a step in which the mutation leading to the neoepitope is ascertained as being located in a cancer driver gene.
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