Methods and apparatus to perform multi-band link aggregation in a wireless network are disclosed. An example apparatus includes a buffer controller to store (A) a first set of data packets that have been received on a first interface and (B) a second set of data packets that have been received on a second interface into a buffer, the first and second sets of data packets being received from a wireless device during a same time frame; and a window determiner to control a first bitmap corresponding to the first set of data packets received on the first interface and a second bitmap corresponding to the second set of data packets received on the second interface, a first size of the first bitmap and a second size of the second bitmap being smaller than a third size of the buffer.