Invention Application
- Patent Title: HETEROCYCLIC COMPOUND
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Application No.: US17630840Application Date: 2020-07-28
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Publication No.: US20220274982A1Publication Date: 2022-09-01
- Inventor: Yuta TANAKA , Yuta TANAKA , Fumiaki KIKUCHI , Takeshi YAMAMOTO , Minoru NAKAMURA , Kazuaki TAKAMI , Masataka MURAKAMI , Masaki DAINI , Yasufumi WADA , Keiko KAKEGAWA , Takahito KASAHARA , Tomohiro OHASHI , Junsi WANG , Zenichi IKEDA , Florian PUENNER , Masaki SETO , Satoshi MIKAMI , Minoru SASAKI
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Chuo-ku, Osaka-shi, Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Chuo-ku, Osaka-shi, Osaka
- Priority: JP2019-139178 20190729
- International Application: PCT/JP2020/028785 WO 20200728
- Main IPC: C07D471/04
- IPC: C07D471/04

Abstract:
The present invention provides a compound having a glucosylceramide synthase inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of lysosomal storage diseases (e.g., Gaucher's disease, Fabry's disease, GM1-gangliosidosis, GM2 activator deficiency, Tay-Sachs disease, Sandhoffs disease), neurodegenerative diseases (e.g., Parkinson's disease, Lewy body dementia, multiple-system atrophy) and the like.
The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.
The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.
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