Invention Application
- Patent Title: MIXED MODE CATION EXCHANGE CHROMATOGRAPHY LIGANDS BASED ON 1,3-DIOXOISOINDOLIN-2-YL STRUCTURES
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Application No.: US17696917Application Date: 2022-03-17
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Publication No.: US20220305460A1Publication Date: 2022-09-29
- Inventor: CHRISTOPHER BELISLE , JIALI LIAO , EDWIN LOZANO
- Applicant: BIO-RAD LABORATORIES, INC.
- Applicant Address: US CA Hercules
- Assignee: BIO-RAD LABORATORIES, INC.
- Current Assignee: BIO-RAD LABORATORIES, INC.
- Current Assignee Address: US CA Hercules
- Main IPC: B01J20/285
- IPC: B01J20/285 ; B01J20/289 ; B01J20/30 ; B01J20/28 ; C07K1/16 ; B01D15/38
Abstract:
The subject invention pertains to proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic 1,3-droxoisoindolin-2-yl group functionalities to a large-pore support matrix, the only linkage between the ligand and the support matrix being a chain having a backbone of one, two, three, four, or five atoms between the hydrophobic group and the support matrix.
Public/Granted literature
- US11731108B2 Mixed mode cation exchange chromatography ligands based on 1,3-dioxoisoindolin-2-yl structures Public/Granted day:2023-08-22
Information query
