发明申请
- 专利标题： CELL CULTURE MEDIA AND METHODS FOR GENERATING HUMAN ALVEOLAR MACROPHAGE-LIKE CELLS
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申请号： US17657344申请日： 2022-03-30
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公开(公告)号： US20220315900A1公开(公告)日： 2022-10-06
- 发明人: Larry S. Schlesinger , Susanta Pahari
- 申请人： TEXAS BIOMEDICAL RESEARCH INSTITUTE
- 申请人地址： US TX San Antonio
- 专利权人： TEXAS BIOMEDICAL RESEARCH INSTITUTE
- 当前专利权人： TEXAS BIOMEDICAL RESEARCH INSTITUTE
- 当前专利权人地址： US TX San Antonio
- 主分类号： C12N5/071
- IPC分类号： C12N5/071
摘要：
Provided here methods of generating human alveolar macrophage-like cells in-vitro from blood-derived monocytes by culturing them in a cell culture medium containing a mixture of a surfactant and two or more cytokines. This mixture can contain calfactant, granulocyte-macrophage colony-stimulating factor, transforming growth factor beta, and interleukin-10.
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