Methods and apparatus for a pixel system for providing power supply noise rejection. A photodetector has a first terminal coupled to a voltage supply and a second terminal and a differential transimpedance amplifier has a first input coupled to the second terminal of the photodetector. The differential transimpedance amplifier is configured to convert a singled ended output on the second terminal of the photodetector to a differential signal. A bias circuit is coupled to the differential transimpedance amplifier to bias the differential transimpedance amplifier and the photodetector.