Methods, systems, and media for rendering immersive video content with foveated meshes are provided. In some embodiments, the method comprises: receiving a video content item; determining, using a hardware processor, whether the video content item meets at least one criterion; in response to determining that the video content item meets the at least one criterion, generating, using the hardware processor, a foveated mesh in accordance with a foveation ratio parameter on which frames of the video content item are to be projected, wherein the foveated mesh has a non-uniform position map that increases pixel density in a central portion of each frame of the video content item in comparison with peripheral portions of each frame of the video content item; and storing the video content item in a file format that includes the generated foveated mesh, wherein the immersive video content is rendered by applying the video content item as a texture to the generated foveated mesh.