A cockpit pressurization and oxygen warning system includes a cabin pressure input and an aircraft pressure input. A pilot interface includes a first visual indicator having a first recognizable characteristic disposed in a first position that is made visually perceptible when a first signal is asserted and a second visual indicator having a second recognizable characteristic esthetically different from the first recognizable characteristic and disposed in a second position different from the first position that is made visually perceptible when a second signal is asserted. A control circuit that is responsive to the cabin pressure input and the aircraft pressure input determines an acceptable range for the cabin altitude that corresponds to the aircraft altitude. The control circuit asserts the first signal when the cabin altitude is within the acceptable range and asserts the second signal when the cabin altitude is not within the acceptable range.