Invention Application
- Patent Title: BENZIMIDAZOLE INHIBITORS OF PAD ENZYMES
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Application No.: US17265840Application Date: 2019-08-07
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Publication No.: US20220348562A1Publication Date: 2022-11-03
- Inventor: Khehyong Ngu
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- International Application: PCT/US2019/045459 WO 20190807
- Main IPC: C07D403/14
- IPC: C07D403/14 ; A61K31/506 ; C07D471/04 ; A61K31/497 ; C07D401/14 ; A61K31/437 ; A61K31/4439 ; C07D417/14 ; C07D413/14 ; A61K31/4184 ; C07D409/14 ; A61K31/427 ; A61K31/4192 ; A61K31/4196 ; A61K31/422 ; A61K31/438

Abstract:
The present invention provides compounds of Formula (I): or a pharmaceutically acceptable salt thereof, useful as inhibitors of PAD4, compositions thereof, and methods of treating PAD4-related disorders. Variables rings A, B, R1, R3, R8, and other variables are as defined herein.
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