Methods and systems for nulling in wireless communication networks are disclosed herein. In one embodiment, a method performed by a first wireless communication node for initiating a nulling transmission includes: transmitting a control message to be received by a second wireless communication node, wherein the control message informs the second wireless communication node to initiate the nulling transmission toward a first station; and transmitting data to the first station during transmission of the nulling transmission from the second wireless communication node to the first station.