- 专利标题: METABOLIC ENGINEERING FOR MICROBIAL PRODUCTION OF TERPENOID PRODUCTS
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申请号: US17729056申请日: 2022-04-26
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公开(公告)号: US20220364127A1公开(公告)日: 2022-11-17
- 发明人: Ajikumar Parayil KUMARAN , Chin-Giaw LIM , Souvik GHOSH , Christopher PIRIE , Jason DONALD , Aaron LOVE , Hong NAN , Hsien-Chung TSENG , Christine Nicole S. SANTOS , Ryan PHILIPPE
- 申请人: MANUS BIO INC.
- 申请人地址: US MA CAMBRIDGE
- 专利权人: MANUS BIO INC.
- 当前专利权人: MANUS BIO INC.
- 当前专利权人地址: US MA CAMBRIDGE
- 主分类号: C12P5/00
- IPC分类号: C12P5/00 ; C12N9/02 ; C12N9/04 ; C12N9/10
摘要:
In various aspects and embodiments, the invention relates to bacterial strains and methods for making terpene and terpenoid products. The invention provides bacterial strains with improved carbon flux through the MEP pathway, to thereby increase terpene and/or terpenoid product yield by fermentation with carbon sources such as glucose.
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