- 专利标题: BIHETEROCYCLIC COMPOUND
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申请号: US17870955申请日: 2022-07-22
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公开(公告)号: US20220380353A1公开(公告)日: 2022-12-01
- 发明人: Hitoshi WATANABE , Yoshiaki ISOBE , Hidenori KIMURA , Yuji FUJIWARA
- 申请人: SUMITOMO PHARMA CO., LTD.
- 申请人地址: JP Osaka
- 专利权人: SUMITOMO PHARMA CO., LTD.
- 当前专利权人: SUMITOMO PHARMA CO., LTD.
- 当前专利权人地址: JP Osaka
- 优先权: JP2016-006205 20160115,JP2016-173510 20160906
- 主分类号: C07D405/14
- IPC分类号: C07D405/14 ; A61K31/352 ; A61K31/4192 ; A61K31/4709 ; A61K31/519 ; C07D311/22 ; C07D405/04 ; C07D471/04 ; A61P25/28 ; A61P27/04
摘要:
The present invention provides a compound of formula (1) and a pharmaceutical composition comprising the compound useful as a nerve regeneration promoter wherein R1-L- is R1—OC(O)—, or the like, R1 is hydrogen atom, optionally-substituted C1-6 alkyl group, optionally-substituted 3- to 8-membered cycloalkyl group, or the like, R2 is hydrogen atom or the like, Ring A is formula (2) or formula (3) wherein R3 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like, the part of X, Y, and Z is X=Y-Z, X-Y=Z, or X-Y-Z, X is nitrogen atom, NR4 (R4 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like), or the like, Y is carbon atom or the like, and Z is carbon atom, nitrogen atom or the like.